Heat-based transdermal delivery of a ramipril loaded cream for treating hypertension

Heat-based transdermal delivery of a ramipril loaded cream for treating hypertension

Heat-based transdermal delivery of a ramipril loaded cream for treating hypertension

In this collaborative work, Anna Voronova (Univ. Lille) and STiBNite ESR Diego Jaramillo (device fabrication, UCLouvain) present the delivery of an angiotensin-converting enzyme (ACE) inhibitor, ramipril, using an electrothermal actuator based on a gold nanowire array to increase the transdermal ramipril flux. Using rats as in vivo model, systolic and diastolic blood pressure were monitored, while heat activation in the electrothermal actuator provided full drug delivery.

The full paper can be found here.

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